施敏 研究员 

中国科学院上海有机化学研究所

金属有机化学国家重点实验室 

上海市零陵路345号,200032

电话: +86 21 54925137

传真: +86 21 64166128

邮箱:mshi@sioc.ac.cn

教育:

1988.04 - 1991.03   日本大阪大学工学部,获博士学位

1985.10 - 1988.03   日本歧阜大学工业化学系,获硕士学位

1980.09 - 1984.07   华东理工大学精细化工系,获学士学位

工作经历:

1998.04 -      进有机所工作,担任课题组长和博士生导师

1996.12 - 1998.03   日本科学技术振兴事业团,从事博士后的研究工作

1993.04 - 1995.10   日本歧阜药科大学药品合成化学研究室,助教

1995.10 - 1996.12   美国俄克拉亥玛大学从事博士后的研究工作

1991.04 - 1993.03   日本歧阜Shellac高分子材料公司开发部,技术员

研究领域:
  • 绿色化学-二氧化碳的固定,小分子活化,环境友好的硝化反应,在超临界二氧化碳流体中的化学反应
  • 手性催化-新型的手性配体的合成,不对称Morita-Baylis-Hillman反应的研究,有机小分子催化的反应研究
  • 金属有机化学-基于张力分子的新基元反应的开发

获奖及荣誉:

2005年礼来科研成就奖

职务:
课题组长

代表论著  

1.  Song Yang, Kang-Hua Rui, Xiang-Ying Tang, Qin Xu,Min Shi*Rhodium/Silver Synergistic Catalysis in Highly Enantioselective Cycloisomerization/Cross Coupling of Keto-Vinylidenecyclopropanes with Terminal Alkynes. J. Am. Chem. Soc.2017,139, 5957-5964.

2.Qiang Wang, Xiang-Ying Tang*,Min Shi*Metal-Free Cross-coupling of Arylboronic acid and Derivatives with DAST-type reagents for the Direct Access of Diverse Aromatic Sulfinamides and Sulfonamides.Angew. Chem. Int. Ed.2016,55, 10811-10815.

 

 

3.Liang-Yong Mei, Yin Wei,Xiang-Ying Tang*,Min Shi*Catalyst-dependent Stereodivergent and Regioselective Synthesis of Indole-fused Heterocycles through Formal Cycloadditions of Indolyl-allenes.J. Am. Chem. Soc.2015,137, 8131-8137.

4. Xiao-Nan Zhang, Gen-Qiang Chen, Xiang-Ying Tang, Yin Wei,Min Shi*Phosphine-Catalyzed Annulations of 4,4-Dicyano-2-Methylenebut-3-Enoates with Maleimides and Maleic Anhydride.Angew. Chem. Int. Ed.2014,53, 10768-10773.  

5. Gen-Qiang Chen, Xiao-Nan Zhang, Yin Wei, Xiang-Ying Tang*Min Shi*Catalyst Dependent Divergent Synthesis of Pyrroles from 3-Alkynyl Imine Derivatives: Non-carbonylative and Carbonylative Approach.Angew. Chem., Int. Ed.2014,53, 8492-8497. 

 

6.  Kai Chen, Zi-Zhong Zhu,Yong-Sheng Zhang,Xiang-Ying Tang*, Min Shi*RhII-Catalyzed Intramolecular Cycloisomerizations of Methylenecyclopropanes withN-sulfonyl 1,2,3-triazoles.Angew. Chem., Int. Ed.2014,53, 6645-6649. 

 

7. Di-Han Zhang, Xiang-Ying Tang*,Min Shi*Gold-catalyzed tandem reactions of methylenecyclopropanes and vinylidenecyclopropanes.Acc. Chem. Res.2014,47, 913-924.   

   

 

8. Jin-Ming Yang, Cheng-Zhi Zhu,Xiang-Ying Tang*, Min Shi*Rhodium(II)-Catalyzed Intramolecular Annulation of 1-Sulfonyl-1,2,3-triazoles with Pyrrole and Indole rings: Facile Synthesis ofN-bridgehead Azepine Skeletons.Angew. Chem. Int. Ed.2014,53, 5142-5146. 

 

9. Long Huang, Hai-Bin Yang, Di-Han Zhang, Zhen Zhang, Xiang-Ying Tang, Qin Xu*, Min Shi*Gold-Catalyzed Intramolecular Regio- and Enantioselective Cycloisomerization of 1,1-Bisindolyl-5-alkynes.Angew. Chem., Int. Ed.2013,52, 6767-6771.  

 

10.  PeiC.-K, Jiang Y, Wei Y,Shi M*Enantioselective Synthesis of Highly Functionalized Phosphonate Substituted Pyrans or Dihydropyrans: Asymmetric [4+2] Cycloaddition ofb,g-Unsaturateda-Ketophosphonates with Allenic Esters.Angew. Chem., Int. Ed.2012,51, 11328-11332. 

 

11.  ShiM*, LuJ-M, WeiY,Shao L-XRapid generation of molecular complexity in the Lewis or Br?nsted acid-mediated reactions of methylenecyclopropanes.Acc. Chem. Res.2012,45, 641-652. 

 

12. Lu B-L, Dai L-Z,Shi M*Strained Small Rings in Gold-Catalyzed Rapid Chemical Transformations.Chem. Soc. Rev.2012,41, 3318-3339 

 

 

13. Lu B-L,ShiM*Synthesis of Functionalized Polycyclic Compounds by Rh(I)-catalyzed Intramolecular Cycloaddition of Yne-VDCPs and Ene-VDCPs.Angew. Chem., Int. Ed.2011,50, 12027-12031.  

 

14. Zhu Z-B, Wei Y,Shi M*Recent Developments of Cyclopropene Chemistry.Chem. Soc. Rev.2011,40, 5534-5563 

 

15. Zhang D-H, Yao L-F, Wei Y,Shi M* Gold(I)-Catalyzed Cycloisomerization of 1,6-Diynes Containing Propargylic Ester and Arenyne: Synthesis of 2,3-Disubstituted 3-Pyrroline Derivatives.Angew. Chem., Int. Ed.2011,50, 2583-2588.